Publications

CAST 1. Zefang Tang#, Shuchen Luo#, Hu Zeng, Jiahao Huang, Xin Sui, Morgan Wu, and Xiao Wang* Search and match across spatial omics samples at single-cell resolution. Nature Methods 21, 10, 1818-1829 (2024) . doi: 10.1038/s41592-024-02410-7 [ PubMed ] [ Full Text ]

GEPIA series 2. Zefang Tang#, Boxi Kang#, Chenwei Li, Tianxiang Chen, and Zemin Zhang* GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis. Nucleic Acids Research 47, W1, W556-W560 (2019) . doi: 10.1093/nar/gkz430 [ PubMed ] [ Full Text ]

3. Zefang Tang#, Chenwei Li#, Boxi Kang, Ge Gao, Cheng Li, and Zemin Zhang* GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Research 45, W1, W98-W102 (2017) . doi: 10.1093/nar/gkx247 [ PubMed ] [ Full Text ]

Disease Network 4. Zefang Tang*, Yiqin Yu, Kenney Ng, Daby Sow, Jianying Hu, and Jing Mei* Disease network delineates the disease progression profile of cardiovascular diseases. Journal of Biomedical Informatics 115, 103686 (2021) . doi: 10.1016/j.jbi.2021.103686 [ PubMed ] [ Full Text ]

1. Zefang Tang*, Tianxiang Chen, Xianwen Ren, and Zemin Zhang* Identification of transcriptional isoforms associated with survival in cancer patient. Journal of Genetics and Genomics 46, 9, 413-421 (2019) . doi: 10.1016/j.jgg.2019.08.003 [ PubMed ] [ Full Text ]

2. Zefang Tang*, Chenwei Li, Karena Zhang, Mingyu Yang, and Xueda Hu* GE-mini: a mobile APP for large-scale gene expression visualization. Bioinformatics 33, 6, 941-943 (2017) . doi: 10.1093/bioinformatics/btw775 [ PubMed ] [ Full Text ]

3. Chenwei Li#, Zefang Tang#, Wenjie Zhang, Zhaochen Ye, and Fenglin Liu* GEPIA2021: integrating multiple deconvolution-based analysis into GEPIA. Nucleic Acids Research 49, W1, W242-W246 (2021) . doi: 10.1093/nar/gkab418 [ PubMed ] [ Full Text ]

4. Hu Zeng#, Jiahao Huang#, Jingyi Ren#, Connie Kangni Wang, Zefang Tang, Haowen Zhou, Yiming Zhou, Hailing Shi, Abhishek Aditham, Xin Sui, Hongyu Chen, Jennifer A. Lo, and Xiao Wang* Spatially resolved single-cell translatomics at molecular resolution. Science 380, 6652 (2023) . doi: 10.1126/science.add3067 [ PubMed ] [ Full Text ]

5. Hailing Shi#, Yichun He#, Yiming Zhou#, Jiahao Huang, Kamal Maher, Brandon Wang, Zefang Tang, Shuchen Luo, Peng Tan, Morgan Wu, Zuwan Lin, Jingyi Ren, Yaman Thapa, Xin Tang, Ken Y. Chan, Benjamin E. Deverman, Hao Shen, Albert Liu, Jia Liu*, and Xiao Wang* Spatial atlas of the mouse central nervous system at molecular resolution. Nature 622, 7983, 552-561 (2023) . doi: 10.1038/s41586-023-06569-5 [ PubMed ] [ Full Text ]

6. Xin Sui#, Jennifer A. Lo#, Shuchen Luo, Yichun He, Zefang Tang, Zuwan Lin, Dániel L. Barabási, Yiming Zhou, Wendy Xueyi Wang, Jia Liu, and Xiao Wang* Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks. Nature Methods 22, 12, 2574-2584 (2025) . doi: 10.1038/s41592-025-02867-0 [ PubMed ] [ Full Text ]

7. Hu Zeng#, Jiahao Huang#, Haowen Zhou#, William J. Meilandt, Borislav Dejanovic, Yiming Zhou, Christopher J. Bohlen, Seung-Hye Lee, Jingyi Ren, Albert Liu, Zefang Tang, Hao Sheng, Jia Liu, Morgan Sheng*, and Xiao Wang* Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease. Nature Neuroscience 26, 3, 430-446 (2023) . doi: 10.1038/s41593-022-01251-x [ PubMed ] [ Full Text ]

8. Li Che, Wenna Chi, Yu Qiao, Jie Zhang, Xinhua Song, Ye Liu, Lei Li, Jiaoyuan Jia, Maria G. Pilo, Jingxiao Wang, Antonio Cigliano, Zhilong Ma, Wenhua Kuang, Zefang Tang, Zemin Zhang, Guanghou Shui, Silvia Ribback, Frank Dombrowski, Matthias Evert, Rosa Maria Pascale, Carla Cossu, Giovanni Mario Pes, Timothy F. Osborne, Diego F. Calvisi, Xin Chen, and Ligong Chen* Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. Gut 69, 1, 177-186 (2020) . doi: 10.1136/gutjnl-2018-317581 [ PubMed ] [ Full Text ]

9. Yapeng Ji, Chuanzhen Yang, Zefang Tang, Yongfeng Yang, Yonglu Tian, Hongwei Yao, Xi Zhu, Zeming Zhang, Jiafu Ji, and Xiaofeng Zheng* Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. Nature Communications 8, 15308 (2017) . doi: 10.1038/ncomms15308 [ PubMed ] [ Full Text ]

10. Ruidan Xu, Shuyu Yu, Dan Zhu, Xinping Huang, Yuqi Xu, Yimin Lao, Yonglu Tian, Jinfang Zhang, Zefang Tang, Zemin Zhang, Jing Yi, Hong-Hu Zhu, and Xiaofeng Zheng* hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy. Nature Communications 10, 1, 3812 (2019) . doi: 10.1038/s41467-019-11795-5 [ PubMed ] [ Full Text ]

11. Chuanzhen Yang, Weicheng Zang, Zefang Tang, Yapeng Ji, Ruidan Xu, Yongfeng Yang, Aiping Luo, Bin Hu, Zemin Zhang, Zhihua Liu, and Xiaofeng Zheng* A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy. Cancer Research 78, 4, 1069-1082 (2018) . doi: 10.1158/0008-5472.CAN-17-2143 [ PubMed ] [ Full Text ]

12. Dan Zhu, Ruidan Xu, Xinping Huang, Zefang Tang, Yonglu Tian, Jinfang Zhang, and Xiaofeng Zheng* Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1. Cell Death and Differentiation 28, 6, 1773-1789 (2021) . doi: 10.1038/s41418-020-00700-z [ PubMed ] [ Full Text ]

13. Jinyao Zhang, Zhaoli Chen, Zefang Tang, Jianbing Huang, Xueda Hu*, and Jie He* RNA editing is induced by type I interferon in esophageal squamous cell carcinoma. Tumour Biology 39, 7 (2017) . doi: 10.1177/1010428317708546 [ PubMed ] [ Full Text ]

14. Yichun He, Hao Sheng, Hailing Shi, Wendy Xueyi Wang, Zefang Tang, Jia Liu*, and Xiao Wang* Towards a universal spatial molecular atlas of the mouse brain. bioRxiv (2024) . doi: 10.1101/2024.05.27.594872 [ BioRxiv ] [ Full Text ]